Coffee powers our days—and sometimes, even nights. Even the thought of coffee motivates me to get out of bed most mornings! According to a 2014 review from Food and Chemical Toxicology, approximately 85% of the U.S. population1 consumes at least one caffeinated beverage a day, so it’s no overstatement to say that America runs on the stuff. But with all of this talk about caffeine keeping us awake, you can’t help but wonder what it’s doing to your sleep hygiene. This energizing phytonutrient and antioxidant is found in coffee and tea but also in things like chocolate, soda, and even some nootropic supplements. Understanding how caffeine affects your body is essential to reaping the benefits of this long-used phytochemical2 and avoiding the less desirable side effects, like suboptimal sleep. Most caffeine (i.e., the instant-release stuff) is fully absorbed 45 minutes after being ingested but doesn’t leave the body for a while. According to Kogan, the full metabolism of caffeine can take up to 10 hours. The less common, extended varieties of caffeine intentionally prolong the release of caffeine3 over time, sustaining its levels in the blood and its benefits while buffering against the dreaded “crash” phenomenon. This also means you would want to take it earlier in the day so the energizing effects don’t bleed into your nighttime ritual. As you can imagine, not everyone metabolizes caffeine the same, which results in discrepancies between individual experiences. Caffeine sensitivity depends on age, sex, genetic makeup, and environmental factors (e.g., whether the person smokes or is pregnant), shares Broderick. As mentioned, your genes have a profound effect on your sensitivity to caffeine, too. “Variations in the CYP1A2 and AHR genes have been shown to affect how quickly the body metabolizes caffeine. Research has also shown that people with a variation in their ADORA2A gene experience stronger caffeine effects and for longer periods of time,” Kogan notes. A classic 8-ounce cup of coffee contains about 96 milligrams4 of caffeine. But honestly, most of us are more likely to reach for 16 ounces of brewed coffee or cold brew, which have double the caffeine content. A 2018 review states that the average American adult consumes about 200 milligrams5 of caffeine every day, confirming this hypothesis. focus+ supplies 150 milligrams of caffeine per capsule, straight from the Coffea robusta and Coffea arabica species of the coffee plant. This includes 50 milligrams of caffeine instantly released into your system via antioxidant-rich whole coffee fruit, as well as 100 milligrams of sustained-release caffeine (Xtenergy) delivered throughout the day via green coffee beans.* According to Deshanie Rai, Ph.D., FACN, the vice president of OmniActive Scientific & Regulatory Affairs, “Leveraging patented technology, Xtenergy from green coffee beans is clinically shown to sustain caffeine release in the body3—extending its nootropic benefits and buffering against the infamous ‘crash’ phenomenon.”* In other words, this thoughtfully delivered caffeine has been clinically shown to increase alertness, relaxation, and overall mood, while simultaneously combating jitteriness, tenseness, and tiredness.* (Talk about useful plant bioactive technology). This focus-enhancing supplement also contains L-theanine, which is the amino acid responsible for the calm, focused state often felt with matcha.* And while the benefits are the same as the green-tea-famous bioactive, the concentrated dose of L-theanine found in focus+ is intentionally derived via a pure, patented fermentation process. (It also happens to be the most clinically researched type of L-theanine, aka Suntheanine®). So, when should you stop drinking caffeine during the day? “Research from the Journal of Sleep Medicine7 indicates that a general guideline for most individuals is to cut off caffeine intake at least six hours before bed,” says Kogan. For the extended-delivery varieties of caffeine, you might consider backing that cutoff time further. Caffeine timing is ultimately a personalized decision. Indeed, with such variation in how people metabolize caffeine, Kogan advises personal trial and error to find the best time to cut off their intake. For example, those who are especially sensitive to caffeine should limit their use to the morning. Plus, it’s important to remember the other foods and drinks that contain caffeine (like chocolate and soda) to ensure you’re really going caffeine-free when you intend to. Kogan also shares that even though there aren’t many ways to speed up caffeine metabolism, some things can be helpful in avoiding unpleasant side effects, like increasing water intake. Because caffeine has diuretic effects, drinking adequate amounts of water is vital to feeling good while consuming caffeine. She recommends eating well-balanced and fiber-rich meals before consuming caffeine, too, to slow the absorption, leading to fewer side effects related to too much caffeine intake. Strangely, these sound a lot like the things we all try to avoid by consuming caffeine in the first place, which can get us into a whole mess. For some more sensitive folks, consuming even as little caffeine as just a daily cup of coffee can cause these effects9 when it’s skipped. Talk about a vicious cycle! If you’re looking to end the cycle, experts agree that having a strict cutoff time for your last cup of coffee or tea (approximately six hours before you go to bed), and being mindful of other caffeinated foods and supplements you might be consuming is key. Maybe even skip the midday coffee for an herbal tea. Alternatively, a supplement with sustained-release caffeine—like mbg’s focus+—may be the key to eliminating that caffeine crash (and the need for that afternoon coffee) entirely.*